Key Benefits
• Inhibits estrogen-deficiency-induced weight gain
• Lowers serum total cholesterol (TC)
• Reduces IL-6 levels in adipose tissue
• Increases serum estradiol levels
• Upregulates estrogen receptor (ER) expression
• Promotes SCFA production in feces
Key Data
• Weight gain: 5.66 ± 1.802 g (CCFM1180 group) vs. 10.83 ± 2.025 g (model group) – 47.8% reduction
• Serum TC reduced by 12.57% vs. model group
• IL-6 levels reduced by 68.53% vs. model group – alleviates obesity, diabetes, and non-alcoholic fatty liver disease
• Serum estradiol: 17.54 ± 1.836 ng/L (CCFM1180) vs. 15.27 ± 0.4353 ng/L (model group)
• Upregulates ER expression in adipose tissue, relieving menopause-related symptoms
Patent
National Invention Patent – A Lactobacillus plantarum strain for alleviating metabolic disorders and obesity caused by estrogen deficiency and its application
Commercial Use
Already used in multiple beauty & weight management probiotic blends
Why Choose CCFM1180?
Specifically targets estrogen-deficiency-induced metabolic decline – a unique niche rarely addressed by other probiotic strains
Clinically relevant for peri‑ and post‑menopausal women – a fast‑growing demographic in the health & wellness market
Multi‑action profile: weight control + lipid reduction + anti‑inflammation + hormone regulation – ideal for multifunctional women‘s health formulas
Strong data support with clear quantitative results – easy to translate into compelling label claims
